slug for the region is not empty, I think you mean the city slug
space and any character will be removed..so can just update database table copy s_name to s_slug!
if your region are empty,try to enter manually slug in database!
how many region do u have?30-40-50? this dont take to long time to fill that field...
for city slug, if u have 3000 city in your database a manually work is not the best solution!